16 Shadman II Chohan Tower Opposite Kinnaird College Jail Road Lahore.

0311-1797 111
0321-4443922
042 35961039

24/7 Customer Support

Non Hodgkin Lymphoma

Overview

What is the Lymphoma?

The lymphocytes, which are white blood cells that fight infection, start to multiply abnormally and begin to collect in certain parts of the lymphatic system, such as the lymph nodes (glands).

What is Non-Hodgkin Lymphoma?

Non-Hodgkin’s lymphoma is a lymphatic malignancy, where tumours begin to develop from the lymphocytes or white blood cells; this condition affects the immune functions within the body. It has a higher prevalence than Hodgkin’s lymphoma. In Pakistan, non-Hodgkin’s lymphoma is one of the top ten cancers.

Causes

Researchers have discovered that non-Hodgkin’s lymphoma is associated with a few risk factors in general, but the exact causes of the disease are still unknown.  The following are some of the things that may raise an individual’s chances of developing NHL:
Age: With age increases the risk of developing non-Hodgkin’s lymphoma.
Immunosuppressants: Prolonged usage of immunosuppressants may increase the risk of non-Hodgkin’s lymphoma.
Infections: HIV, Epstein-Barr virus, and Helicobacter pylori infections have all been associated with increased risk of non-Hodgkin’s lymphoma.

Diagnosis

In a few cases, non-Hodgkin’s lymphoma disease progresses slowly. On the other hand, a few NHLs progress more readily. Following are the few testing methods used for NHL diagnosis:

a. Medical History and Physical Exam

b. Biopsy

c. Imaging Tests

d. Blood Tests

e. Bone Scan

Treatment

If it is slow-growing non-Hodgkin’s lymphoma, the doctors may recommend monitoring instead of immediate treatment. However, if the condition is aggressive and the tumour is fast-growing, immediate treatment is recommended.
Chemotherapy
Chemotherapy can be used alone or in combination with other treatments like immunotherapy or radiation therapy, depending on the kind and stage of lymphoma. When treating NHL, a combination of chemo drugs is used in order to achieve a better treatment response.
Stem Cell Transplant
Stem cell transplant is one of the treatment options for NHL. High dose chemotherapy not only destroys the cancer cells but also damages the bone marrow cells. Therefore, these bone marrow cells have to be replaced to restore normal blood cell production and other functions.
Immunotherapy
Immunotherapy alters the body’s immune system in such a way that it starts attacking the cancer cells and destroys them. Since NHL is a lymphatic disease, immunotherapy is a promising treatment option with better treatment response.
Targeted Therapy
Targeted therapies are devised based on the unique proteins present on the cancer cell’s surface, specific genes and tumour environment – which are responsible for the growth and survival of cancer cells. Targeted therapy halts the tumour growth and destroys the cancer cells using multiple mechanisms.
Radiation Therapy
For people with stage 1 and stage 2 non-Hodgkin’s lymphoma, radiation therapy is administered as primary treatment. Radiation therapy and chemotherapy are frequently used in combination to treat advanced lymphomas. It is also used as a part of palliative care in terminally-ill patients.
Surgery
Surgery is a rarely used treatment line for non-Hodgkin’s lymphoma. It may be performed to collect the biopsy sample. Surgery may also be considered for the management of lymphomas in the spleen, thyroid gland and stomach.

Book an Appointment Today?

Treat Cancer in Right Way

Scroll to Top